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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b15e6419b5a0fb1f1986235f6a9d043594db0dfe349add48eb1e2ce1d0d4b0c' 
  AND token = '4CUwW0DFSD1zT54igUbP9r+lJ9sHlwQLvQWdpFRY5q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}