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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886a3101908a4af4ed662c5e9276df5f1855fa135d2fdb6efdf8b4f7f9807fa9' 
  AND token = 'MA6bvp6C4tLo2hj3RSB84JJQpUkBUGGMl1xVkQ4wO5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}