SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db4141f7741aa51a15e95c93a8fbc256b7482ed55ed0167583d72d4a7d42442' 
  AND token = 'SIKAGj+imdbW7PaCZWpyL17EfBeW5rDxvc0Y4k/XjA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}