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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eba891cdac8b26f0d8964032f8cd3e15dd0769ea23bb716e5ca4138308e1a04' 
  AND token = 'lDCjgRA9+VIvzWSx+Wic8fjs4QXCfCbSfnrwUDAGb8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}