SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5abf08a33807c1edc03da6de313e89d4084759a8125a5fdbb71fb5fae1c923' 
  AND token = 'JkErrH3LHI9wOvvHWX7qa7umieHwwNA81HBlih1T2tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}