SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca35f0f20171ba08aee92221599b881d101397ced27c1ad539cf0678bfe6850' 
  AND token = 'Q60/NPP5X6xe27yMFOEUpjRJQBEI+QCHNLGoTEE96WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}