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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0716310730019d89ce67b44bddb14555540f189e82ff8f7f779d76f00ca2a61' 
  AND token = 'PzyPpP9r5Z5sJdSyKzg7UZgLPD7lk9CMuYenq/pXWx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}