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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7bd6bba3a4b791c48b9f1cac20b23bb2d5ff75da82d8d9292e33dde9385fd1' 
  AND token = 'EoX38olkxaBziWPboXXI2ivscHGMwkls117lzMiSccc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}