SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae88aa3be5fe70a5eebfd6cf5522a45ab8045c2b81007d7152106dee6c916d02' 
  AND token = 'IIV4WOK1s/6nX8v6NODdy63Uhmo4Nhdh7BfsNc+dOYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}