SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d63df595d0849e84d39646f3845b645e8ba2ff7909a4391438a4e8bca84cca' 
  AND token = 'UZzx2lFVxl7Spw/53I8fSuEvW1NDyTYj7UEP7WLcMQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}