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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5061b2f9fda794dec00f4af3ce8a87c69f5ef9d93e810ab408e500cd4a7e332f' 
  AND token = 'UaRBftn+ghMNInO8oL4Np0LZOd4y4AKMWT4iaUMjFNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}