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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1461834d1637a0133611c7f0a1442f6c5e39883d4afb67a04b71e85ec231027' 
  AND token = 'fQ65Vpt+28JXCuMQNxeun2s3POR6/0D1BGwl9Akf/rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}