SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2586a5a085f58fce9ce9eb57dddcf7478de5ede5c96c57c28656c1ce88aa1c1b' 
  AND token = 'T3bdOHc4FRZ3KI6rK847rPh3MSna+rF9KqeqMwUu1Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}