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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7274720fc31f323b74d536b205fb4ae601829511052c34d532beed7bdad2fba' 
  AND token = 'SMV59NzJjT86f9ynYadi3RL0pFKfpTj3S9uwc3dbxaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}