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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0db02fe8e987e2310e4e00eddd1a1864e3e6c6b89063efd8f16f480e0f6cb45b' 
  AND token = 'XkVwHGzjvaQdR2mypTx6y6NFYRQiGNj8UDcS5jxtPZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}