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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e667b63c5a9d496157c6e074af6ce4f30f3bac573ca8b9882e8650b9d2495c7' 
  AND token = 'nN4TT9pgyUHrA/ZYoHVz8oWEoXaxAsUj3KA2dB0CeoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}