SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1d975543a12994dfec3681ae20ec45ebea8f326b83ec607836ee63397c8aae' 
  AND token = 'P8nDt6IEgYsh2zJuVJZmt+a/L2j15AyJNY8s0u1ZLnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}