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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1363c58d859b6f3c41db67331abcd0db2fd988886163228e39f46f79c1e10d38' 
  AND token = 'LziZ97RzQiZ2W2DlaaW0eZM1+GjrOngjnH2fhWyND0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}