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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7340dc1d00678a0728b063888e0fb98ae50975e0867b77f8042a8e151b5c1c81' 
  AND token = '1KAs4hxfJpYQDVckwCJ/oxBUKS4DSwW32uvWWY7JGSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}