SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1c89b61f8b45fe9cd6b636e191954900c41245ee1c922248b748d489795e2b' 
  AND token = '1w/c9/1ypj7S7cKJWz8pFuVgCf5DvHb3UPRDEZB3oZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}