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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724d5e61a0a24e5812e6c9d0e57cafe185ade0cb4704080887afa051d110a99a' 
  AND token = 'd2pzdj+CGwhh4yWGXBj01375F9D3V43cWzpmxlBnm4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}