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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60a6c3034637ec1179054a12f5ca638968d96c406371c96124c855780046f521' 
  AND token = 's2yl0LGcg0357mY0sxG90NN0apRlyTrNBuZgFKbuNvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}