SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbb8d4dbcceaa5a43c2d5bdd555e4a978fe105de7a78404b8b7340023c14d869' 
  AND token = 'oQJ9xtLkaqvTD5JEcHc5oz8kOIOmoRCA+VSIAt9JrlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}