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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2db32f4e212dd840068f7da260bae32fbc8c40fe728b6352c75d9a266e7b0ad' 
  AND token = 'nNPg4z4CqbVo6No0C3Uh/8X//7LR2MJ3XyTblMMhV0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}