SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b5eded9233d728dbaa76acfc0ad427f6a66d7380f9ef549e5f5c2c0f31a46d' 
  AND token = 'EIRT9t41r++r+WI0g1jjGSGq0jd4yY65r6S5iqssAHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}