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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2a95cc6219e01bc8f1af2b7249b87bf0c9a02c215a36dfa0844eb431e3e949' 
  AND token = 'I2FoFjiyOYdwhHYgXavG4klNlz8fkS59uHUft8RKaTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}