SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6024ddfa30b15f7fc175211f236ba2961df786b72b2d24f317fa870d7e048f71' 
  AND token = 'H01k4hbLoSoujcXb/TmiqObuG63cSIIMpN1TG1amfXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}