SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee9743e7ab4261e781534854e6b17d033020203013875fcb0e4775eb547af0cb' 
  AND token = '9pnZWlnW0VtqHRQgXh+waPPz7jwPscmp6Pbdr+5FAQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}