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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0499ab396174e9691a5733e604eddcaa4dc67daeb26fa2b820a5c15f07686146' 
  AND token = 'x3fDEepXDeKQP4BKC0McEF1y3RkzOHTpQ7f6Fhf3VUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}