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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4608333844aca72180a560bb56d5bf92c4a7b6781ccb83d3cd230814fcc5821d' 
  AND token = '3udu2JHuVGn1zKX7zqW+YB8k7pzald0eKXJrTN/13Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}