SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159f81df4da7f2d5f41bc6ec134a616b399b2226dfd950ba574edd9c3cee9bb1' 
  AND token = '3rrmk0l8RhySOWQibxfBjlOSjVnnfsJ27CyMOQLk6sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}