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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43caf0826014076f0c02cdf934d8f0f06335ef62ddeaca3f873b48300d8ef1e4' 
  AND token = '1UuQmJH+qR4bbXRC6bnBwpLPY85luxcctVX7U9+hNiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}