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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ef05c0726b360af6ceae89f56cb362598b89638b0dc85f495b4eb5ba1756f3' 
  AND token = 'cEkdpDWymjJYwF1qpzWfAjGvqEMAfCQsDcSvG6Hh2sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}