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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e79dc4944b0b61310a1387ce650fdea8c62ac9682c5e36a5f579deb8b0f017' 
  AND token = 'TlpHWa86XTnbLVX4vVNaujCJX/TQ10EmVTLQsAMJfxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}