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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d1a502618c64c348d9855aa27a9b316a0bfca7f257c756af9498e3ac9dfd1d' 
  AND token = 's9+ClK54/iBtKQB/oQulsT5Q4KsH5fWt8ay9t9waiS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}