SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4760db2f8cea9ca14023beb2bad95996a828d4c82de91fc0f899c91bd1021b1c' 
  AND token = 'GokMTlh4VcHWnrDQdBqOZo6P7XQmn7dvsX/6bF6I1iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}