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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45490c82d2273417bf73fbf9ce2f3d1d0fdbe728fbb92f4bd7e242a343b8f6a7' 
  AND token = 'WYyp5PhIco/hyt0T2541XpUbpfVzvLQ1HK9m2BEG04I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}