SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00086019a95d6186d21a1331a999d17461ba1eb3b8dd6bd2c205fd2e8ad03150' 
  AND token = '2j9c/lyUYzbEzj2DcEPnFVdeJLkSe9oUxxdDN0zOjlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}