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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25aa72e7774626c25889ddfd69823f1beedf13b5d535358671bcb7e55bf6b28' 
  AND token = 'O4hYOE93lHj1jVOgnU5hj0hNJu5rq2IDPgsfzjR8NRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}