SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124c8c7c2c456fb804cfe3c8608caebe3f1d81f03dc1f13b0a7b46b33b062493' 
  AND token = 'QkwRR9w6h6z8kjn2qNRjzrgdCs3j0VU4qArfxOnQ/hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}