SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b0414ef20fb70a5bf8b4fb592b81279c3bb10282e594db34f954cd697c6b67' 
  AND token = 'ATzvpUlFk+CRktKtY/79mpCZW9xPsQHEC9If8aUABj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}