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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80af81c5b96bf5c5771176e8cb7545d8cf99a75691b6fb73f910253c556727d0' 
  AND token = 'gI76w3kCg9vxPhF0horHojYkxq0pv3kx4bX9o2EKG7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}