SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e275a5425c46e6f11648816426a94e2c354eb0b41d5c95cf5ee1cfa97d12d92' 
  AND token = 'p/3p/0RRT+dMQowQlSme5+SbRebUBrUZBeqw00C1Nbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}