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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f48ce7f6f51b802dafb5f90405126d37677f72c3501913d20c6b9cf7f750f46f' 
  AND token = 'LA9cRo+O99TNVGQCrvHGDkurC4RGNzmfHk0fQbdYEiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}