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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b623f3e044892c45289706e31a8ed8e9e5ca2be8f341fec2c9b125b49a7b3a' 
  AND token = 'vPNRD9XaNa3I2OcZNv7knQOkaeSJkVqD71MDa1tIl+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}