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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27209317ee34d9e101cbe355e06ab1e8017768039e3e02541ed21d4821136dc2' 
  AND token = 'OyEfCK+TSlpP/IczcDc4EXG2rQuKtUg16ZJvv6umHQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}