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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5110e3c154f0dcc97961c8bc3005e90cda29e43f44796f4019e5b47ff52c9634' 
  AND token = 'aQ7m5PCxKRpw4NwD5QGEhNbIWbNtNKLXMVKohf+h8Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00090

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}