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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '190ab6491ae6513a17e7858bfb0f4b09003d9b62c3d13353b566b677bcffa2a0' 
  AND token = '67bDS3xr1QKpXonxjbpNnGBUzIfMlLlFKh8HpwpXcIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}