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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0407254f197d7bb49548dc8fb496964e0c3c9f918e009218c75b3e093ef398' 
  AND token = 'ktW2JclKj4ggJ625E+OgQP6gQHhkMw9PTmgdTTTy0QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}