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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7c22f9fc78de0bedc229fbb39fcd9a724b54e7d80b7b1e896a77942b1f71089' 
  AND token = 'DBGET2zQYB9H8Y4p/CbFDB1N+r3C5qVc5Gp/Ln35f4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}